What really is Cervical Cancer?

The third of its kind, this blog talks about the progression and development of the infection once it turns into invasive cancer. 

Cancer as a disease impacts the cells of our body in a way due to which they start to grow uncontrollably, crowding over healthy cells. Every cell in our body has a specific role to perform, but, when cancerous cells start to grow, they hinder this required working of the healthy cells giving rise to problems in the affected area of the body. 

Cancer usually has a progressive growth. It starts from the initial place of origin and as it grows untreated, it starts affecting the nearby tissues and organs. Cancer also has the ability to spread to different parts of the body through blood, lymph or tissue, called metastasis. 

CERVICAL CANCER  

Cancer in the cervix, a part of the female reproductive system, is called cervical (SERR-vick-el) cancer. It is often confused with the term cervical (serr-VAIK-el), which means pertaining to the neck. 


THE CERVIX

Cervix is the lower part of the uterus that connects it to the vagina. It is primarily made up of connective tissue and muscle and has two types of cells. 

  • Glandular cells – They are tall, column like and are found in the endocervix (the part of the cervix leading to the uterus). These are involved in the production of cervical mucus. 
  • Squamous cells – They are flat and thin and are found in the ectocervix (the part of the cervix leading to the vagina) and the vagina. 

Cancer of the cervix impact these cells. They can be found in the form of carcinomas (malignant cancer cells) divided primarily into the following types, 

  • Squamous cell carcinomas – Nine out of ten of cervical cancers are found to be squamous cell carcinomas. As the name suggests they affect the squamous cell types in the vagina. 
  • Adenocarcinomas – They form from the mucous producing glands and have become more common in the last few years. 
  • Adenosquamous or mixed carcinomas – These are the least common type of cancer and has the properties of both. 

STAGES OF CERVICAL CANCER
The onset of cervical cancer begins with changes and abnormalities in the cells of the cervix, commonly known as dysplasia. These abnormal cells over a period of time may develop into full-fledged invasive cancer.
Just like any other type of cancer, stages of cervical cancer can be defined on the basis of the extent of the spread of the cancer.

  • Carcinoma in Situ – It marks the very beginning of cervical cancer in which abnormal cells are found in the lining of the cervix. These abnormal cells have the potential to become cancerous in the future. It is also sometimes referred to as Stage 0.
  • Stage 1 – By this time, the abnormal cells have developed into cancer. But, it is still restricted to the cervix. Stage 1 can further be classified into sub-stages depending on the size of the tumor. The tumors during this stage generally range from anywhere near 3 millimeters to 4 centimeters wide.
  • Stage 2 – The cancer has spread to the surrounding tissue yet is contained within the pelvic wall. It still has not reached the lower third of the vagina.
  • Stage 3 – The pelvic wall and the lower third of the vagina have been affected by the cancer in this stage. The cancer may also have started to affect the functioning of the kidneys.
  • Stage 4 – By the time the cancer reaches the fourth stage it has spread beyond the pelvic wall and can also be seen in the lining of the bladder or the rectum. The cancer may also have started to metastasize and reach other parts of the body like the liver, lungs, bones and lymph nodes.

Cervical cancer may also reappear after it has been treated. The recurrence of the cancer can happen in any part of the body other than the cervix. 

We cannot reiterate enough that cervical cancer is the only preventable cancer, provided it is detected and treated timely. Why delay it any further! Why take the risk of being just another statistic! Take the reign of your health into your own hands 

Visit your gynaecologist now and help CAPED create a Cervical Cancer Mukt Bharat. 

Author : Taru Medha (CAPED Intern)

Bibliography/Resources :
http://cancerindia.org.in/cervical-cancer/

https://www.cancer.gov/types/cervical/patient/cervical-prevention-pdq

https://www.nhs.uk/conditions/cervical-cancer/causes/

https://www.cancer.org/cancer/cervical-cancer.html



He initiated TQM as a management way in SRF and the Company has so far earned the Deming Prize for two of its businesses, for the tyre cord in 2004 and for the Chemicals Business in 2012.

Mr. Bharat Ram was elected President of Confederation of Indian Industry (CII) during 2000-2001 and continued to play important roles as Chair and Member of various council of CII till March 2015. He co-chaired the Indo German Consultative Group (IGCG) which consisted of eminent citizens from both the countries from 2002 till 2014.

Mr. Bharat Ram is actively involved in social development activities. Currently he is Chairman of:

  • SRF Foundation, the social wing of SRF, which manages its own schools and also supports education in villages;
  • The Lady Shri Ram College (LSR) for Women in Delhi which has consistently been rated as one of the two best colleges of India;
  • The Shri Ram Schools; and
  • CAF (India) – Charities Aid Foundation (India); and
  • A governing body member of CAPED– a registered Society for spreading cancer awareness program

He is on the governing body of SPIC Macay, a society for the promotion of the Indian Classical Music. He is himself an accomplished sitar player, having learnt it from Pt. Ravi Shanker.

Mr. Arun Bharat Ram has won many awards and accolades, The Jamshedji Tata Award, which was conferred on him by the Indian Society for Quality (ISQ) for the year 2006 and the Officer’s Cross of the Order of Merit, presented by the Federal Government of Germany in 2008. Mr. Bharat Ram schooled at the Doon School, Dehra Dun and graduated in Industrial Engineering from the University of Michigan, U.S.A.

Prior to his current appointment, Dr. Vaid practiced and coordinated the Department of Medical Oncology at the Rajiv Gandhi Cancer Institute and Research Centre (RGCI) in Rohini, Delhi, India. In addition to his active medical oncology practice, Dr. Vaid has participated in many national and international clinical trials as a principal and sub-investigator. His clinical interests include Hemato-Oncology and Bone Marrow Transplant. He has also taken keen interest in treating breast cancer, lung cancer and genitor-urinary cancers.

Dr. Vaid established the bone marrow transplant services in the private sector in Delhi starting with Rajiv Gandhi Cancer Institute & Research Centre during the last decade and has cumulatively carried out the largest number of bone marrow transplants in the private sector in Delhi. Currently at Medanta, he leads a large team which comprises of hemato-oncologists, pediatric transplant specialists, hemato pathologists specializing in transplant pathology, transfusion specialists, and molecular pathologists required for HLA typing and post transplant chimerism monitoring.

Dr. Vaid lectures nationally and internationally and has contributed to numerous peer-reviewed articles, book chapters and abstracts. His work has appeared in Journal of Clinical Oncology, Journal of Thoracic Oncology, World Journal of Gastroenterology and Hepatobiliary Pancreatic Diseases International. Dr. Vaid currently chairs the Indian Council of Medical Research Subcommittee on formulating guidelines for treatment of Hodgkin’s Disease in India. He is recognized as Teacher and Examiner for superspeciality course of Medical Oncology by National Board of Examinations and the Bombay University and a reviewer of thesis for award of PhD degree in Life Sciences, Chhatrapati Shahu Ji Maharaj University, Kanpur, India. He is an editorial board member for the following journals “Research & Reviews: A Journal of Medicine” and “Research & Reviews: A Journal of Toxicology”, and “South Asian Journal of Cancer”.

He was conferred the prestigious “Padma Shree” Award, one of the highest civilian award in India, by the President of India in 2009 for his contribution to the field of medicine on 14th April, 2009.
Prior to Stellaris, Alok was a Partner at another VC firm, Helion Ventures, where he led enterprise software and services investments. Before his career in venture capital, Alok was the Chief Operating Officer (COO) of SAP India and had been associated with SAP since the year 2004 in various leadership roles in the United States and in India. Before SAP, Alok also worked with Siebel Systems, The McKenna Group, McKinsey & Company and Cadence Design Systems.

Alok has completed his MBA from INSEAD (France), MS in Computer Sciences from University of Texas, Austin and his B.Tech in Computer Science from IIT Delhi.

Alok is interested in cricket, light & classical Indian music, hiking and long distance running. In addition, Alok is passionate about mathematical puzzles and used to run a weekly blog at http://alokgoyal1971.com/.

Alok’s association with cancer started in 2007 when his mother was diagnosed with a late stage Ovarian Cancer. He saw his mother battle with cancer for more than four years, during which time he was the primary care giver.

Committees / Ambassador Radhika is a part of many committees in CII and is also Pinkathon Ambassador. Social Initiatives

  • Radhika has participated in plays as a lead singer to raise funds for NGO’s like Azad Foundation and CAPED.
  • Mamma Mia Again, ABBA songs Musical, was staged at The Shri Ram Center, Delhi in December 2016 to raise funds for Azad Foundation.
  • I have a Dream, ABBA songs Musical, was staged at Apparel House, Gurgaon to raise funds for CAPED in April 2017.
  • I have a Dream, ABBA songs Musical, was staged at The Shri Ram Center, Delhi to raise funds for CAPED in December 2017.
  • She was also instrumental in staging a play, Khushi Ek Ehsaas, by the visually impaired children of JPM School to raise funds for Blind Relief Association at Kamani Auditorium in January 2016.

Hobbies

  • Radhika learns music at Theme.
  • She also loves to run and has completed 3 half Marathons in India in 2017.

Amitav worked for Bristol Myers Squibb based in Princeton for 5 years. He has been involved with his family-run business since 1994.

Amitav was educated at the Doon School and went on to study Economics at St. Stephens College, Delhi University. He has an MBA from UNC Chapel Hill, USA. He sits on the board of Central Square Foundation, AVPN India and several other non/for-profit organisations in India.

In 2010, he became an Aspen Fellow, in 2015 he became an Ashoka Fellow and 2017 he was incubated as an N/Core Fellow.

Organizational Positions
  • Vice President, Fertility Preservation society of India/ 2014 – 2018
  • Coordinator, Deptt of Obstetrics and Gynaecology, Artemis Hospital, Gurgaon, April 2007 – Nov 2009
  • Coordinator, (North India), Clinical Research Committee, Federation of Obstetrics & Gynecology Society of India (FOGSI) 2003-2008
  • Executive Member, Adolescent committee, Association of Obstetrics & Gynaecologists of Delhi (AOGD ) 2006 – 2007
  • Executive Member, Association of Gynaecologic Oncologist of India,2009 -2011
  • Chairperson, Gynaec. Oncology Committee, Gurgaon Obstetrics and Gynaecology Society, 2011
  • Executive Member, Gynaec.Oncology Committee, Association of Obstetrician & Gynaecologists of Delhi (AOGD) 2012 -2014
  • Executive Member, Gurgaon Obstetrics and Gynaecology Society (GOGS), 2012 -2013
  • Coordinator – Young Women Club ( National Project under the aegis of National Adolescent Health Committee, FOGSI) 2012 -2013
  • Treasurer, Asia Oceania Research Organization in Genital infections and Neoplasia ( AOGIN) –India, 2011 -2015
  • Executive member, Gynaec Oncology Committee, Federation of Obstetrics & Gynecology Society of India (FOGSI).2012 -2015
  • Peer Reviewer for the Journal of Federation of Obstetrics & Gynecology Society of India (FOGSI).
  • Peer Reviewer for The Indian Journal of Gynaecologic Oncology.
  • Invited as a trainer by Vattikuti Foundation, Michigan, USA for – Gynaec. Robotic Surgery Training of Gynaecologists at KIMS Vattikuti Institute of Robotic Surgery, Hyderabad
  • Executive member, AOGD(Association of Obsterician and Gynaecologist of Delhi ) 2013 – 2014
  • Executive member, AOGD(Association of Obsterician and Gynaecologist of Delhi ) 2014-2015
  • Executive member,GOGS 2013
  • Executive member, Gynaec.Oncology Committee, Association of Obstetrician & Gynaecologists of Delhi (AOGD) 2013 -2014
  • Executive member, Gynaec.Endoscopy Committee, Association of Obstetrician & Gynaecologists of Delhi (AOGD) 2013 -2014
  • Executive member, International academic exchange committee(FOGSI) 2013 – 2015
  • Executive member, Delhi Society of Gynaec endoscopists.2014- 2015
  • Co-Chairperson, Gynaec.Oncology Committee, Association of Obstetrician & Gynaecologists of Delhi (AOGD) 2015 -2016
  • Executive member, Gynaec Oncology Committee, Federation of Obstetrics & Gynecology Society of India (FOGSI).2015 -2017